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Drugs, OTCs, Herbals and Hepatotoxicity

Drug-induced toxicity is the leading cause of acute liver failure and acute hepatitis in the United States. Prescription drugs such as amoxicillin-clavulanic acid, troglitazone, antiretrovirals, angiotensin receptor blockers (ARBs), angiotensin-converting enzyme inhibitors (ACE-I), anti-diabetic agents (acarbose, gliclazide, metfomin, and insulin), anticonvulsants, antiepileptics, and other psychotropics (e.g. selective-serotonin reuptake inhibitors [SSRIs]) have all been implicated in liver damage.

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